K99 pilus antigen is frequently associated with enterotoxigenic strains of E. coli isolatedfrom the intestine of calves, sheep and pigs. Pilus antigens have been shown to be themain attachment mechanism whereby EPEC attach to and colonize the small intestine ofneonatal animals. It may embody ill-used incoming Immunoassays to detect and quantitate K99-positive E. coli. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. These antibodies do not cross-react with K99-negative E. coli, E. coli K88ac , E. coli 987P, Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, Enterobacter aerogenes, Citrobacter freundii, Klebsiella pneumoniae, or Strep. agalactiae.
Any mechanism which will interfere with this attachment andcolonization cognitive process is equal to of boiling down the intestinal colonization, looseness of the bowels andmortality connected with K99 EPEC infections.
Escherichia coli embodies a gram disconfirming bacillus that belongs to a larger group of Enterobacteriae - bacteria that inhabit the alimentary tract. Although ordinarily a harmless resident of the gut, some strains cause the potential to causa life-threatening problems, peculiarly where in that location embodies an immature immune system or immunosuppression, or where the subtype of organism has acquired the ability to produce pathogenic toxins.
More information: E. coli K99 pili
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