Monday, March 26, 2012

What is Novobiocin Sodium Salt?

Novobiocin Sodium Salt
CAS:1476-53-5
MF:C31H35NaO11
MW: 634.61
Content:≥90.0%
Titer:≥850mcg/mg
Properties:Powder
Storage temp.:2~8℃
Specification;BR
Novobiocin, also known as albamycin or cathomycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides a member of the order Actinobacteria . Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin).
Clinical Use
Novobiocin is active against Staphylococcus epidermidis and may be used to differentiate it from the other coagulase-negative Staphylococcus saprophyticus, which is resistant to novobiocin, in culture.
Novobiocin was licenced for clinical use under the tradename Albamycin (Pharmacia And Upjohn) in the 1960s. Its efficacy has been demonstrated in preclinical and clinical trials. It has since been withdrawn from the market. Novobiocin is effective antistaphylococcal agent used in the treatment of MRSA
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