Side effects of 5-Fluorouracil

5-Fluorouracil is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.  5-fluorouracil is classified as an "antimetabolite."
Use
Colon and rectal cancer.
Breast cancer.
Gastrointestinal cancers including: anal, esphageal, pancreas and gastric (stomach).
Head and neck cancer
Hepatoma (liver cancer).
Ovarian cancer.
Topical use (cream or solution) in basal cell cancer of the skin and actinic keratoses. -see document fluorouracil(cream).
Side effects of 5-Fluorouracil
Important things to remember about the side effects of fluorouracil:
Most people do not experience all of the side effects listed.
Side effects are often predictable in terms of their onset and duration.
Side effects are almost always reversible and will go away after treatment is complete.
There are many options to help minimize or prevent side effects.
There is no relationship between the presence or severity of side effects and the effectiveness of the medication.
The side effects of fluorouracil and their severity depend a variety of factors including dosage, the individual's metabolism, other drugs given as part of a combination therapy, and/or the schedule and duration of treatment.
Fluorouracil (5-FU or f5U) (sold beneath the cast names Adrucil, Carac, Efudix, Efudex and Fluoroplex) is a biologic that is a pyrimidine analog which is acclimated in the analysis of cancer. It is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase. It belongs to the ancestors of drugs alleged antimetabolites. It is about administered with leucovorin.
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